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Description
GLP-1 RAs mimic naturally occurring GLP-1, an enterohormone produced in response to oral intake that regulates glucose metabolism and promotes weight loss

Long-term semaglutide use (12+ months) has been studied and shows sustained safety and efficacy for weight loss maintenance in clinical trials

2008;295(3):R87480

doi: 10.2741/3805 83 SmithARnnekleivOKellyM

In clinical trials, patients taking semaglutide lost an average of approximately 15% of their body weight over 68 weeks
