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BMP-2 and -Catenin were significantly increased, and the increase was more significant at high doses ( in vivo study explains that semaglutide may improve bone metabolism through regulation of the Wnt/-catenin signalling pathway, which is consistent with our previous results

Thus, the onset of action was very much delayed, and a steady state was not reached until 810 weeks of treatment [17,18]

This effect may be linked to the higher baseline lipid levels typically seen in overweight or obese patients and the influence of semaglutide and metformin on dietary habits [29]

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J., Stewart, D