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Patients with obesity, hypertension, lipid disorders and various other risk factors have significantly increased rates of complications (Nauck et al., 2021b)

4 A 2025 systematic review examining GLP-1 receptor agonists for depression found that several observational studies showed reduced depressive symptoms in people taking these medications, though results from randomised controlled trials were more mixed

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Vagal innervation of intestine contributes to weight loss after Roux-en-Y gastric bypass surgery in rats

I hold on to the hope that one day proven human trials will lead to real GLP-1 patches that can safely deliver what so many are searching for