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Published 2019 Aug 9

SGLT2 inhibitors were not as dramatic as the differences between GLP-1s and insulin/metformin, a finding that surprised Fuemmeler

Short-acting GLP-1RAs (exenatide [ t 1/2 of 2.4 hours] and lixisenatide [ t 1/2 of 24 hours] administered before meals twice-daily and once-daily, respectively) exhibit intermittent GLP-1 receptor activation translating into potent deceleration of upper gastrointestinal motility, an effect which is sustained during prolonged treatment

Grausland et al

Estos mecanismos en conjunto ayudan a disminuir el consumo excesivo de caloras y a favorecer la prdida de peso de manera gradual
