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Trial data have also noted a transient, modest increase in heart rate, and mild elevations in pancreatic enzymes (lipase and amylase) in some participants

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"Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract." Current Pharmaceutical Design , 2011

Lipophilic compounds can become trapped in the mucus rather than diffusing through to the epithelium, reducing absorption efficiency