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Mice with no access to food during the activity phase (dark phase) of a 12-h light/12-h dark cycle had a significantly slower tumor progression and higher survival compared with mice that had no access to food during the inactivity phase (light phase), and mice that had access to food ad libitum 13

Side effects may last longer if: The starting dose is too high Dose increases happen too quickly The body doesnt have enough time to adjust between changes A slower, personalized dosing approach often reduces both the severity and duration of side effects

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