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Sohrabi M, Floden AM, Manocha GD, Klug MG, Combs CK (2020) IGF-1R inhibitor ameliorates neuroinflammation in an Alzheimers disease transgenic mouse model

Glucagon-like peptide-1 (GLP-1)-based receptor agonists as a treatment for Parkinsons disease

TGF1, via its downstream Ras homolog family member A (RhoA)/rho-associated coiled coil-containing protein kinase (ROCK) signaling pathway, stimulates the abnormal distribution of F-actin and G-actin and stress fiber accumulation, creating a barrier for GLP-1 secretion
Following medical guidance and allowing time for dose adjustments can also help maximize results
