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Albanese MJ, Pies R

HARMONY 3: 104-Week Randomized, Double-Blind, Placebo- and Active-Controlled Trial Assessing the Efficacy and Safety of Albiglutide Compared With Placebo, Sitagliptin, and Glimepiride in Patients With Type 2 Diabetes Taking Metformin

[1] Long-term adherence, not macronutrient ratio, was the decisive factor in weight-loss outcomes. Sacks FM et al

However, as millions of individuals have turned to semaglutide and tirzepatide for weight reduction, a surge of adverse event reports involving users developing severe gastrointestinal issues after taking Ozempic, Wegovy, Rybelsus and Mounjaro have been reported

However, compounded medications are not themselves FDA-approved as finished products and have not been individually evaluated by the FDA for safety, efficacy, or quality