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Overview of the Chemistry, Pharmacokinetic Profiles, and Pharmacodynamic Mechanisms of DPP4 Inhibitors DPP4is are a diverse group of small molecules that vary in their chemical structure, pharmacokinetic properties, including absorption, distribution, metabolism, and excretion pathways, and pharmacodynamic attributes, such as the potency and selectivity of DPP4 inhibition [66, 71, 72]
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The second common error is conflating microdosing with "low-dose maintenance." Microdosing is a titration strategy
The primary outcome measure is time to first major cardiovascular event over five years of follow-up
