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Were it to be approved, it would be the first medication to activate three metabolic hormone receptors at onceGLP-1, GIP, and glucagon

About 26% of the metformin and 14% of the placebo groups had lost greater than or equal to 5% of their initial body weight at the end of year two

What is the risk of muscle loss during GLP-1 research

The clinical data supporting their effectiveness was generated in studies where participants also followed reduced-calorie diets and exercise programs
T.ZhuW.et al
