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However, the business declined, and on 4 May 2023, the company announced that it was going out of business after 40 years

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Intracranial tumors including craniopharyngiomas, germinomas, gliomas, hamartomas, and pituitary adenomas can lead to hypothalamic injury either directly or as a complication of their treatment
Notably, the effectiveness and safety of lixisenatide are virtually not affected in moderate renal insufficiency patients [52]

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