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The authors attribute these results to the increase in GLP-1, although it was not directly measured (Furrer, Kaufmann, Tschuor, Reusch & Lutz, 2010)

When caloric intake is substantially reduceda common occurrence given semaglutide's potent effects on appetite and satietythe body shifts from primarily using glucose for energy to breaking down stored fat

GLP-1 is primarily released after eating, but some people find a consistent overnight eating window helps appetite and glucose patterns indirectly

Childhood obesity and adult cardiovascular disease risk factors: a systematic review with meta-analysis

Start the medication first, stabilize on it, then add Pendulum at half dose