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Understanding the best times to take each medication can make using them together safer and more effective

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These include past cases of pancreatitis, medullary thyroid cancer, or major gastrointestinal issues

The crude residue was purified by silica gel flash column chromatography ( n -heptane:EtOAc, 2:1) yielding 4-nitrophenyl (2-(pyridin-2-yldisulfaneyl)ethyl) carbonate (89%)

The short answer is it can in some people, but fatigue is not considered one of the most common reported effects