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Commun 12, 5165 (2021)

For many patients, gastrointestinal side effects, including sulfur burps, diminish significantly after 8-12 weeks as physiologic adaptation occurs

Fatigue: The most common cause of fatigue during weight loss is not eating enough

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Participants had to have: BMI 40 1 obesity-related comorbidity (OSA, HTN, CVD, dyslipidemia) Documented failure of lifestyle interventions Almost 69% were female , average age 52 years , and mean BMI 46.3