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Manage Your Stress Chronic stress can contribute to emotional eating and weight gain

doi:10.1111/j.1463-1326.2012.01663.x 17

Moreover, both endogenous GLP-1 and GLP-1RAs interact with circumventricular organs (CVOs), such as the area postrema and subfornical organ, which lack a fully intact BBB

As most discontinuations occurred during the rapid dose-escalation period of treatment, slower up-titration of dose may counter these

This article examines the emerging evidence, proposed mechanisms involving brain reward pathways, and important safety considerations for clinicians and patients navigating this investigational area
