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The section on the adrenal medulla covers this response in more detail
In order to investigate the functional targeting of -cells by the aGLP1-E2 conjugate, we used Min6 insulin-secreting cells transfected with a luciferase reporter construct containing an estrogen response element (ERE-Luc) 7

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doi: 10.1007/s00125-016-4061-x

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