glp 1 drugs anti inflammatory 2024 Multiple Sclerosis Highlight Popular GLP-1 medications may have

With the effects seen of the GLP-1 family of drugs on preventing kidney damage in diabetes, liver disease (non-alcoholic or metabolic-associated steatosis, NASH/MASH), and addiction, this drug class is exceeding all expectations

Theyve since become popular as weight loss drugs

Nevertheless, our findings suggest that liraglutide-induced FGF21 promotes weight loss in the presence of high carbohydrate diets via its actions on the central nervous system

These drugs fall within two categories: human GLP-1 backbone agents (that is, albiglutide, dulaglutide, liraglutide and semaglutide) and exendin-4 backbone agents (that is, exenatide, lixisenatide and tirzepatidethe latter activating both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors) 1

Available from: 4 Morgan Stanley, 2023