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GLP-1 receptors are distributed throughout the central nervous system, including in the hypothalamus and the mesolimbic reward system the very dopamine-rich pathways involved in craving, motivation and emotional eating

Marketed as Ozempic, semaglutide is a glucagon-like peptide-1 (GLP-1) analogue that is used to treat diabetes and for weight management

(3) A possible modulating interplay between the previously mentioned two pathways.

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