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Diet and Exercise Healthy eating and activity are recommended

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The net effect is profound: clinical trial participants lost an average of 24.2% of their body weight over 48 weeks at the highest tested dose

Close monitoring of lupus disease activity, laboratory parameters (including renal function, inflammatory markers, and autoantibody titers), and adverse effects is essential during Semaglutide treatment

Unfortunately, metformin has no data regarding improvement in liver enzymes and histology in NASH/NAFLD, although it is associated with a reduced incidence of HCC and extrahepatic malignancies