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Over time, obstructive sleep apnea can cause serious cardiac disease and serious neurologic problems, in terms of mental awareness and falling asleep easily during the day, Ren-Fielding said

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Through several mechanisms, including direct interaction with SUR1 and membrane depolarization, intracellular calcium mobilization, and insulin granule priming modification, EPAC2 activation may promote the exocytosis of insulin granules [55, 56]

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