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Interestingly, several studies have demonstrated that exendin-4 has neurotrophic and neuroprotective effects and that it enhances neurogenesis and neural proliferation (Li et al., 2009
Competing interests: All authors have completed the ICMJE uniform disclosure form at and declare: this study was funded by the Canadian Institutes of Health Research
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However, it remains unclear whether improvements result primarily from appetite suppression, altered reward processing, or both
