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In their meta-analysis, Monami et al also considered the occurrence of any major cardiovascular event, a composite end point of CV death, stroke, nonfatal myocardial infarction, heart failure, or acute coronary syndrome

However, when patients stop taking these drugs, they not only regain weight, but, according to a new study, they also incur increased risk of heart attack, stroke and death compared to staying on the medication

In 2019, Teva and Novo Nordisk reached a settlement on the US patent litigation case for liraglutide, allowing Teva to launch a generic version of liraglutide beginning March 22, 2023, unless the liraglutide patents were no longer in force or another generic version of liraglutide was marketed

Bringing addiction treatment 'inside the house of medicine' In addition to food addiction, GLP-1s show promise for opioid, alcohol and nicotine addiction Early studies suggest that GLP-1s may be effective in treating opioid, alcohol and nicotine addiction

However, metformin is also commonly used to treat women with PCOS with infertility or T2DM in pregnancy
