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However, important questions remain about their precise mechanisms of action, potential adverse effects, and which patient subgroups are most likely to benefit

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Randomized participants follow an 8-week dose escalation regimen (3 mg [weeks 04], 7 mg [weeks 48], and 14 mg [weeks 8156])
Patients with a history of GORD, hiatus hernia, or BMI above 35 are already at elevated reflux risk

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