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These results are the basis for a positioning of the DPP-4 inhibitors as second-line therapy for the treatment of type 2 diabetes, especially, when hypoglycaemia should strictly be avoided (see section below)

These findings support continued clinical evaluation of AMG 133

GLP-1R are present in human coronary artery endothelial cells [61]

Abdi AM, Pasiou E, Konstantopoulos P, Driva TS, Kontos A, Papagianni E, et al

g1437 (n=12)