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Within the tirzepatide treatment arm, the studys most common adverse effect, gastrointestinal disorders, occurred in 46.0% of patients who experienced a cardiorenal end point versus 41.4% of patients who did not

Metabolic effects Semaglutides primary metabolic actions stem from its agonism of GLP-1 receptors, widely expressed in pancreatic -cells, the gastrointestinal tract, and the central nervous system

In: Rosenberg RN, Pascual JM, eds

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