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C., Wright, F
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Deng, F

Tirzepatide is a dual-action medication, targeting two different hormone receptors (GLP-1 and GIP) to support weight loss

Specifically, MDL29,951 stimulated calcium flux with 220 nM potency (pEC 50 = 6.660.13) and maximum peak F/F of 0.800.07 in cells expressing hGPR17L, whereas the peak F/F in response to 30 M MDL29,951 treatment was 0.010.01 in control-transduced cells (Figure 1B)

PMID: 16181611