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Key secondary objectives will be to demonstrate the superiority of tirzepatide 5 mg and/or MTD compared to placebo in: (1) maintaining 80% of the body weight reduction achieved during the 60week weightloss period and (2) maintaining 15% body weight reduction for participants who have already lost 15% body weight at randomization (Week 60) including only participants who reached the body weight plateau by the end of the weightloss period (Week 60)

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