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10.1152/ajpendo.00565.2005 113

Thus, the increments in the affinity and activity owing to Glu 22 could be caused by a carboxyl group on Glu adding an extra binding site for the receptor

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From a therapeutic perspective, GLP-1 receptor agonists drugs that mimic the endogenous hormone GLP-1 are used to treat type 2 diabetes and obesity by improving insulin secretion, lowering blood sugar, and supporting weight reduction
