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You should move the medication to your refrigerator as soon as possible

Write it directly on the label with a permanent marker so you never lose track of the 28-day window

You start tirzepatide low, almost always at 2.5 mg once weekly, and titrate up from there regardless of how high your semaglutide dose was

While patients with minimal alcohol use (up to 20/30 g/d in women/men) were enrolled in the ESSENCE trial, those with higher alcohol consumption [ie, in the MetALD (metabolic dysfunction and alcohol-associated liver disease) range] were excluded

Your provider can help you weigh these results alongside other factors Common side effects: The most common side effects for oral semaglutide are nausea and vomiting, while injectable semaglutide most commonly causes nausea and diarrhea