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These gastrointestinal symptoms were generally mild to moderate in severity and tended to diminish over time as patients developed tolerance to the medication

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It is worth noting that pharmacovigilance data, which linked GLP-1 RA administration with ED development, reported tirzepatide in 14.3% of casesa lower proportion compared to liraglutide, dulaglutide, and semaglutide

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Emergency surgery often cannot wait for this washout period, which is why disclosing GLP-1 use to your anesthesiologist before sedation is critical

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Discuss alcohol use, pregnancy plans, pregnancy, or breastfeeding before starting or continuing therapy, because your care plan may need adjustment

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