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Exenatide reduces final infarct size in patients with ST-segment-elevation myocardial infarction and short-duration of ischemia

Subgroup analyses revealed that longer-acting, human GLP-1-based agents, such as dulaglutide and semaglutide, provided more consistent benefits, whereas shorter-acting exendin-4-based agents, like lixisenatide, showed neutral outcomes

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Companies must implement robust quality systems that encompass supplier qualification, incoming material testing, process validation and post market surveillance