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Six months later, shes back in my office, frustrated and defeated

Together, these mechanisms produce a meaningful reduction in appetite and caloric intake
Furthermore, these therapies have been shown to reduce the activation of microglial cells, key immune cells that play a significant role in triggering chronic pain in the central nervous system [36]

Human participants were generally overweight, obese, or insulin-resistant adults, while animal studies predominantly employed diet-induced obese or genetically modified rodent models
