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An early RCT in 44 patients with obesity and subclinical binge eating showed that liraglutide was better than diet and exercise alone in reducing binge-eating scores at 12 weeks 220 , but a later investigation of 27 adults with BED comparing liraglutide against placebo did not find any differences in the number of binging episodes over 17 weeks 218
Food and Drug Administration to put semaglutide and tirzepatide on a list of drugs that are too hard for compounding pharmacies to make
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Given the eminent global opioid crisis, development of GLP-1RA is an important research goal [106]
, The Guardian, , GLP-1 , ( ),
