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Diabetes Obes Metab (2021) 23 Suppl 3:529

Although, as previously mentioned, GLP-1RAs are theoretically associated with medullary thyroid carcinoma, no cases were reported in the RCTs included in our study, either in the tirzepatide or control groups

Both caffeine and alcohol are diuretics

Zepbound and Mounjaro both contain a FDA boxed warning for medullary thyroid cancer, because animal studies of tirzepatide showed that it caused medullary thyroid cancer in rats

Additional SURMOUNT trials confirmed benefits for Type 2 diabetes (SURMOUNT-2), long-term maintenance (SURMOUNT-3), and cardiovascular risk reduction (SURMOUNT-4)