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Apart from this hydrophobic region, it seems that GLP-1R prefers a carboxyl group at the end of the side chain while GIPR can accommodate, but does not favor, an alkaline group

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Oxidative Stress/Angiotensinogen/Renin-Angiotensin System Axis in Patients With Diabetic Nephropathy

These peptides were glucagon-like peptide-1 (GLP-1) and glucagon-like peptide-2 (GLP-2)

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