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Description
The side effect profiles of phentermine and GLP-1 medications are fundamentally different because the drugs operate through entirely different mechanisms, and understanding these differences is essential for making an informed choice

Over time, this can lead to a consistent reduction in daily calorie intake without relying only on extreme dieting or willpower

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This translated to ~15 kg weight loss in treated patients a magnitude approaching bariatric surgery in some cases
30 , 31 , 7577 This may be considered evidence that these drugs could pass through the BBB and activate the neurons in these nuclei