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Common side effects include blue or green discoloration of urine, which almost everyone will notice due to the dye property of the drug

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ADA Standards of Care 2025) recommend that patients with type 2 diabetes and atherosclerotic cardiovascular disease (ASCVD) (or high risk) should be on a GLP-1 RA with proven CV benefit (or an SGLT2 inhibitor) as part of their regimen, independent of A1c, because of the outcome benefits ( [9] ) ( [144] )

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Duloxetine is contraindicated in liver disease causing hepatic impairment and should not be used

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Other factors include concentrated urine due to Mounjaro-induced dehydration

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Strategic hydration (not just drinking more water) Everyone says "drink more water." That advice is incomplete

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