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As a main metabolite of Lachnospiraceae , evodiamine played a role in suppressing osteoclastogenesis in vitro

304 Studies have shown that hordenine decreases the expression of proinflammatory cytokines by suppressing the S1P/S1PR1/STAT3 pathway and promotes the healing of colonic ulcers by regulating the expression of tight junction proteins, including occludin and ZO-1
Action to Control Cardiovascular Risk in Diabetes Follow-On Eye Study Group

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