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Drug Absorption: SNAC integrates into the lipid membrane to increase the uidity of the gastric epithelium, allowing the peptide to enter the systemic circulation through transcellular pathways
Now, their dominance is expanding globally, as more countries begin approving their use for weight loss
Importantly, circulating DPP4 is augmented in obese and type 2 diabetic subjects, and it may represent a molecular link between obesity and vascular dysfunction
Diabetes, Obesity and Metabolism , 22(9), 1454-1467
