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These changes help manage weight and work well with medications
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Baseline glycemic control : Patients with higher HbA1c levels may require more aggressive dose escalation, though this must be balanced against tolerability
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Over the course of 2128 days, SAR425899 evidences maximal BW reduction of 5.32 kg in healthy/overweight patients, while overweight/obese patients with T2D experienced maximal BW reductions of 5.46 kg along with significant reductions in fasting plasma glucose and glycated hemoglobin [177]