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State and federal policymakers are increasingly responding to the issue, including new legislation introduced in Kentucky following a case in which a patient suffered acute liver failure requiring a transplant after taking a compounded weight-loss medication

Rosenstock J, Robins DA, Duffin KL, et al

Neither the Group effect nor an interaction between group and time reached statistical significance, indicating that the GLP-1RA group did not experience significantly different levels of nausea compared to the control group

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But, it can cause gastroparesis, or stomach paralysis, in some users