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Separately, GLP-1 RA pretreatment in Abeta142-treated hippocampal primary cell cultures significantly increased phosphorylated CaMKII alpha -positive cells indicating that GLP-1 RAs may have neuroprotective effects through glutamate receptor-mediated responses.Reference Wang, Wang, Jiang, Yuan, Yu and Li 46 Taken together, GLP-1 RAs may have protective effects against neuropathological changes by promoting neurogenesis and synaptic plasticity

J Endocrinol (2012) 215(3):33546

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doi: 10.1074/jbc.M209423200 42 CampbellJEDruckerDJ
Oral rehydration salts (such as Dioralyte) are recommended by the NHS for replacing lost fluids and electrolytes [8] [9] Avoiding carbonated drinks and alcohol , which can worsen bloating and loose stools From a pharmacological standpoint, dose titration is the most important management tool