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[M]any people lose years trying medications when surgery would have given them a better long-term outcome, he said

Studies show that GLP-1s can lower blood pressure, improve fatty liver disease, and even drastically reduce the progression of kidney disease and the risk of heart attacks and strokes

doi:10.1155/2011/162092 108

Orforglipron is the first oral non-peptide GLP-1 receptor agonist in development for FDA approval to treat weight loss, which could make it more convenient than injectable alternatives 1

This positioning is crucial, as it frames GLP-1 RAs not as first-line treatments but as important tools in a comprehensive management strategy
