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Eli Lilly said on Thursday its experimental obesity drug helped patients lose more than 28 per cent of their weight over a year and a half in a key trial that allows the company to seek regulatory approval and potentially launch the next-generation drug next year.

To qualify, patients must meet one of the following: BMI of 35 or higher BMI of 30 or higher with heart failure, uncontrolled hypertension on two medications, or chronic kidney disease stage 3a or above BMI of 27 or higher with a history of pre-diabetes, prior heart attack, prior stroke, or symptomatic peripheral artery disease That is a meaningfully different population than a standard cash-pay weight loss patient

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In a crossover trial evaluating semaglutide versus placebo as an add-on to automated insulin delivery therapy in adults with type 1 diabetes, the use of semaglutide was associated with an increased percentage of time spent within the target glucose range, along with reduced insulin requirements.

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