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Salameh et al

Since GLP-1 receptor agonists commonly cause nausea, vomiting, diarrhea, and constipationparticularly during dose titrationchoosing a magnesium formulation that doesn't worsen these symptoms is clinically important

Oxidative RNA damage can impair protein translation, and damaged RNA can degrade prematurely, further impairs the synthesis of essential proteins (65)

Therefore, researchers are working toward developing formulations that can be administered once a week, providing a longer-lasting effect and reducing the frequency of injections

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