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Semaglutide a medication originally designed to manage type 2 diabetes has rapidly emerged as a sought-after option for weight loss, celebrated for its ability to support significant and sustained reductions in body weight

All covariates were binary, categorical, or continuous but were essentially guaranteed to exist (more details on TriNetX are in the eAppendix in Supplement 1)

And for a moment, you let yourself wonder: what if this year could actually be different

The key is to choose activities you enjoy and schedule them during times when you feel most energized

If you have diabetes and are taking a GLP-1 medication, make sure your ophthalmologist is aware of your medical history and current medications