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Phase 2 trials used once-weekly subcutaneous injections ranging from 1 mg to 12 mg, with higher doses associated with greater weight reduction but more gastrointestinal side effects

A host of factors need to be considered, including the individuals health status, priorities, comorbidities and other medications, as well as the new drugs cautions and contraindications, side effects, and beneficial effects beyond glucose lowering

KFF recently reported that GLP-1 drug discontinuation was more common in those over 65, although this could change if Medicare begins to cover these medications for those without diabetes

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With any medication, the benefits and risks vary from person to person