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In details, we evidenced separately anthropometric parameters, metabolic effects, changes in biochemical and clinical hyperandrogenism, body composition, and ectopic fat that have been reported in the available randomized controlled clinical trials (RCTs) in PCOS women with overweight/obesity

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Available at: [accessed March 2026]. Phase 3 ESSENCE trial: Semaglutide in metabolic dysfunctionassociated steatohepatitis secondary analyses

Providers will assess whether semaglutide is appropriate based on the underlying cause of weight gain