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Electrolyte monitoring is not routinely required for all GLP-1 users, but becomes essential when patients experience persistent gastrointestinal symptoms or have additional risk factors such as chronic kidney disease, heart failure, age over 65, or concurrent diuretic use

J., Moskowitz J

In contrast, cAMP signaling in response to GLP-1 was comparable between wild-type and mutant receptors, supporting the hypothesis that altered signaling with PF-06882961 was not due to a marked alteration of surface expression for the mutated constructs (Fig

doi: 10.1515/jpem.2011.269 110 GrugniGMarzulloP

Furthermore, we used a commercial glycolysis antibody panel to detect Pfkp, Pyruvate kinase M1 and M2 (Pkm1, Pkm2), Hexokinase 1, Hexokinase 2 and Pyruvate dehydrogenase 1 subunit (Pdh) by immunoblot analysis