semaglutide and alcohol reduces intake relapse-like drinking in male and female rats Does weight loss, diabetes drug

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These results established tirzepatide as the most potent agent in the current pharmacologic armamentarium for obesity

Notably, the target who lost weight and maintained it was rated more favorably (i.e., higher in positive traits, lower in negative traits, less unhealthy) than all three of the targets who currently had obesity (i.e., targets from the GLP-1 regain , diet+exercise regain , and no weight loss conditions), suggesting that having a higher weight is harshly stigmatized regardless of a persons prior weight loss attempts

doi: 10.1021/ja991185g

Some people who take semaglutide report having chest discomfort